HEXAGHEN FastSorb tablets belong to a new class of orally effective IGF-1 (Insulin-Like Growth Factor-1) stimulate compounds.HEXAGHEN uses a FastSorb delivery system for rapid maximum absorption and bioavailability.
HEXAGHEN FastSorb tablets for oral administration containing IGF-1 Optimization synergistic compounds:
GHRP-2 Hexapeptide acetate
cis -4, 17 (20)-pregnadiene-.16 3-dione
trans-4, 17 (20)-pregnadiene-.16 3-dione
The SCIENCE of Insulin-like growth factor-1 (IGF-1) back to top
IGF-1 produced in the body have some unique features and anabolic is one of the most potent natural activators of the AKT signaling pathway, a stimulator of cell growth and multiplication. Watch out for the first time turned to IGF-1 when scientists search for growth hormone (GH) has found that the influence of GH on IGF-1 production was the factor responsible for anabolic effects associated with the administration of growth hormone and natural elevation in the body. In fact, while GH has direct effects of burn fat stored as metabolizes fat, muscle effects are actually attributed to its effects on the increase of IGF-1.Thus, IGF-1 and GH that media not directly muscle cell hyperplasia and muscle growthat the cellular level. IGF-1 is thought to be the main mediator since stimulates differentiation and proliferation of myoblasts (muscle cells), resulting in muscle growth. IGF-1 also increases muscle growth by increasing the absorption of amino acids and protein synthesis.
IGF-1 is a peptide hormone that is involved in the regulation of growth and development of muscle tissue. Its main action is mediated by binding to specific IGF-1 receptors present on many types of cells in many tissues. The free form of IGF-1 fraction is highly bio-active in comparison to IGF-1 binds to IGF binding proteins (ENDOCRINOL METAB 15). IGF-1 is the main mediator of growth hormones in the body. In the cascade of biochemical events leading to an increase in IGF-1 levels of production and, HEXAGHEN is metabolized stimulated growth hormone by the liver and enhances the synthesis and secretion of IGF-1.
Muscle tissue has an abundance of IGF-1 receptors. When serum IGF-1 binds to these receptors on muscle tissue, stimulates anabolic actions and growth processes in humans, including the increase in the number and size of muscle cells:
* REGULATES CELL GROWTH AND DEVELOPMENT.
* REGULATES THE CELLULAR DNA SYNTHESIS.
* MEDIA MUSCLE CELL HYPERPLASIA AND MUSCLE FIBRE DEVELOPMENT INITIATION AND MATURATION.
* IT STIMULATES THE GROWTH AND SIZE OF MUSCLE CELLS.
* STIMULATES GLUCOSE UPTAKE FROM MYOBLASTS (MUSCLE PRECURSOR CELLS), THAT NURTURES THEIR GROWTH AND DEVELOPMENT IN CELLS OF THE MUSCLE FIBRES.
* INCREASES THE SPREAD OF MUSCLE CELLS OF AMINO ACIDS, WHICH ARE USED AS THE BUILDING BLOCKS OF MUSCLE PROTEIN MOLECULES.
* INCREASES NITROGEN RETENTION AND HIGHER FOOD CONVERSION EFFICIENCY.
* REDUCES THE EXCRETION OF NITROGEN.
* IMPROVES WOUND HEALING.
* STIMULATES MUSCLE PROTEIN SYNTHESIS.
* PREFERENTIALLY STIMULATES GROWTH OF LEAN TISSUE.
* STIMULATES MITOGENICA (CELL REPLICATION) THE ACTIVITIES THAT LEAD TO AN INCREASE IN THE NUMBER OF MUSCLE CELLS IN THE BODY.
* VITAL FOR THE REPAIR AND REGENERATION OF MUSCLES.
* CAUSES IMPROVEMENTS IN BODY COMPOSITION, SHOWING A DECREASE IN FAT MASS AND A STRONGINCREASE IN LEAN BODY MASS.
Relationships within the endocrine/IGF-1 axis is a complex system. Scientists have recently identified other factors that play a critical role in affecting the levels of IGF-1. About 98% of IGF-1 is associated with a protein insulin-like growth factor binding different (ENDOCRINOL METAB 15). ENDOCRINOL METAB 15-3, the most abundant protein, represents 80% of all IGF-1 binding. Research has shown that a reduction in IGF-1 binding proteins and maintaining high levels of IGF-1 is related to anabolic effects and muscular development.
As reported in the independent research journals, thyroid function is also associated with improvingand the levels of IGF-1 bio-active tissue and further increase the rate of protein synthesis. Therefore, since the levels of IGF-1 have increased, a number of negative feedback controls involving the thyroid hormone axis will be controlled to maintain the levels of IGF-1 in a tight physiological range, not too high and not too low.By examining the relationship between GH, IGF-1, IGF-1 levels, free IGF-1, ENDOCRINOL METAB 15 and thyroid function, the researchers faced MuscleMeds
This correlation between IGF-1 production and bio-benefits linked to stimulation of the thyroid. synergistic thyroid HEXAGHEN's
involvement is designed to help support more total and free IGF-1 levels for long periods of time, thus prolonging the desired overall
IGF-1 anabolic effects.
Research and development
The muscle building effect of IGF-1 were well known and documented medical for years. But the factors that regulate the body's natural outlet, the researchers questioned. Synthetic IGF-1 was produced by major pharmaceutical biotech companies on a large scale using recombinant DNA technology. These forms of synthesis must be administered by injection of dosage. The development of an effective orally of IGF-1 compound improvement has long been one of the main global goals of biotechnologists.
After years of extensive research and laboratory tests, the researchers found a single MuscleMeds Hexapeptide stimulating IGF-1 (GHRP-2 acetate, Hexapeptide). Thanks to its structure hexapeptide along, developing an effective dosage form for oral GHRP-2 hexapeptide post some biotechnological challenges. Conventional feedingoral (such as tablets, capsules, liquids and capsules) was ineffective due to gastrointestinal tract of hexapeptide-2 GHRP. As with other substances, GHRP-2 peptide hexapetide is subject to destruction (dead) in the gastrointestinal system, which eliminates the effectiveness and ability to achieve the hypothalamo-pituitary. In order to create a product that is suitable for oral administration of GHRP-2 Acetate, Hexapeptide HEXAGHEN scientists employed MuscleMeds using their proprietary technology FastSorb delivery system.
As a result of this research effort based product development, HEXAGHEN has one IGF-1 Complex Optimization. HEXAGHEN novel ingredient composition and properties of liposomal delivery system is designed to stabilize the levels of bioactive compounds for quick absorption and high directly into the bloodstream first through the oral cavity (mouth) of absorption. Delivery times for dosing oral mucosa (transmucosally) is an alternative method of nutrient delivery systemic, which offers several advantages such as the oral mucosa is highly absorptive capacity hogzilla. Therefore, HEXAGHEN of active ingredients are absorbed through the oral mucosa and enter directly into the bloodstream, bypassing the gastrointestinal tract and first-pass metabolism in the liver. This improves the delivery bioeffectiveness in the body, to trigger a series of events: medicated HEXAGHEN stimulates endocrineGH and IGF-1 and supports thyroid function for maximum effects.